Is the SERT gene responsible for OCD? And what is SERT ?
The SERT gene is located on chromoson 17. The SERT codes for a serotonin transporter protein. Its a mutation in the SERT protein that might cause problems – its transportation of the serotonin that is affected. People suffering from OCD, autism, anorexia experience a defective regulation of SERT resulting in proteins are “locked” into the activated state.
But it is importent to note, that this mutation is rare, and not responsible for these disorders in most individuals.
So you can not say that the OCD gene was found….
Read more:
Ozaki N, D Goldman, WH Kaye, et al. 2003.Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Molecular Psychiatry (8): 933-936.
“THE OCD GENE”, Popular Press v. Scientific Literature: Is SERT Responsible for Obsessive-Compulsive Disorder?
BBC Compulsion linked to faulty gene October 2003
BBC Gene for obsessive behaviour September 2002
MSNBC Gene found for obsessive disorder, Mutation affects how body uses serotonin, scientists say November 2003
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